INT219155

Context Info Confidence 0.15 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.23 Pain Relevance 0.10

plasma membrane (HLA-G, LILRB2) signal transduction (LILRB2) extracellular space (LILRB2) cell-cell signaling (LILRB2) cytoplasm (LILRB2)

Anatomy Link Frequency T cells 1 HLA-G (Homo sapiens) LILRB2 (Homo sapiens)

Pain Link Frequency Relevance Heat tolerance 3 81.88 cytokine 11 64.08 Inflammatory response 2 56.64 Multiple sclerosis 1 34.00 psoriasis 7 27.84 Inflammation 16 5.00 agonist 6 5.00 antagonist 6 5.00 chemokine 3 5.00 vagus nerve 2 5.00

Disease Link Frequency Relevance Heat Autoimmune Disease 8 59.04 Communicable Diseases 5 58.44 Cancer 37 57.16 INFLAMMATION 17 56.64 Infection 9 49.12 Disease 24 35.52 Demyelinating Disease 1 34.00 General Immunology 4 32.92 Psoriasis 8 27.84 Acquired Immune Deficiency Syndrome Or Hiv Infection 15 5.00

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Mutation

Event

Anatomy

Negation

Speculation

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Disease term

The binding of HLA-G on T cells with ILT4 on DCs appears to be critical for the differentiation of induction of Tr1 (S Gregori; San Raffaele Telethon Institute, Italy).

HLA-G Binding (binding) of ILT4 in T cells

1) Confidence 0.15 Published 2007 Journal J Transl Med Section Body Doc Link PMC2176053 Disease Relevance 0.23 Pain Relevance 0.10

General Comments

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