INT219156

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.03
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (NLRP3, IL1B) signal transduction (NLRP3, IL1B) extracellular space (IL1B)
aging (IL1B) extracellular region (IL1B) cell-cell signaling (IL1B)
NLRP3 (Homo sapiens)
IL1B (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 16 94.40 High High
antagonist 6 86.40 High High
anakinra 1 84.80 Quite High
vagus nerve 2 77.52 Quite High
agonist 6 55.28 Quite High
cytokine 11 53.44 Quite High
Arthritis 2 32.96 Quite Low
tolerance 3 25.56 Quite Low
psoriasis 7 5.00 Very Low Very Low Very Low
chemokine 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Crystal Associated Disease 4 98.12 Very High Very High Very High
INFLAMMATION 17 94.40 High High
Disease 24 93.36 High High
Syndrome 1 91.60 High High
Shock 1 74.32 Quite High
Injury 1 72.96 Quite High
Diabetes Mellitus 1 54.20 Quite High
Autoimmune Disease 8 42.20 Quite Low
Hodgkin's Disease 1 40.12 Quite Low
Septic Shock 1 34.24 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A constitutively active form of mutated NALP3/cryopyrin, which promotes IL-1?
NALP3 Positive_regulation (promotes) of IL-1
1) Confidence 0.01 Published 2007 Journal J Transl Med Section Body Doc Link PMC2176053 Disease Relevance 1.03 Pain Relevance 0.27

General Comments

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