INT219187

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Context Info
Confidence 0.16
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.37
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (CCR9) signal transducer activity (CCR9)
Anatomy Link Frequency
intestine 2
CCR9 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 6 98.86 Very High Very High Very High
chemokine 3 93.32 High High
Inflammation 16 90.04 High High
psoriasis 7 59.44 Quite High
tolerance 3 46.24 Quite Low
cytokine 11 5.00 Very Low Very Low Very Low
agonist 6 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
vagus nerve 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 24 99.42 Very High Very High Very High
Inflammatory Bowel Disease 2 90.80 High High
Immune System Diseases 1 88.72 High High
Herpes Simplex Virus 2 87.76 High High
Influenza Virus Infection 1 86.80 High High
Purpura 1 85.76 High High
Mucocutaneous Lymph Node Syndrome 1 83.36 Quite High
Systemic Lupus Erythematosus 7 78.04 Quite High
INFLAMMATION 17 77.28 Quite High
Autoimmune Disease 8 63.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The administration of a small molecule antagonist of CCR9 reduces the disease severity in mouse models by blocking CCR9+ T cell migration to the intestine (M Walters, ChemoCentryx).
Negative_regulation (blocking) of CCR9 Binding (migration) of in intestine associated with antagonist and disease
1) Confidence 0.16 Published 2007 Journal J Transl Med Section Body Doc Link PMC2176053 Disease Relevance 1.37 Pain Relevance 0.38

General Comments

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