INT219223

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Context Info
Confidence 0.02
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 5
Disease Relevance 3.24
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
plasma 4
blood 3
eyes 2
liver 1
Ighv10-3 (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 5 42.52 Quite Low
cytokine 5 5.00 Very Low Very Low Very Low
Inflammation 5 5.00 Very Low Very Low Very Low
alcohol 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 280 99.88 Very High Very High Very High
Corneal Opacity 65 90.00 High High
Congenital Anomalies 50 50.00 Quite Low
Cataract 50 36.72 Quite Low
Mydriatic 5 23.52 Low Low
Adhesions 30 5.00 Very Low Very Low Very Low
Eye Disease 15 5.00 Very Low Very Low Very Low
Corneal Disease 10 5.00 Very Low Very Low Very Low
Adenocarcinoma 5 5.00 Very Low Very Low Very Low
Injury 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A high level of hßigh3 expression was also observed by western blot analysis in the plasma of transgenic mice (Figure 1E).
Positive_regulation (level) of Gene_expression (expression) of igh3 in plasma associated with targeted disruption
1) Confidence 0.02 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2185514 Disease Relevance 0.66 Pain Relevance 0
Gross phenotype and electron microscopic examination of the mice eyes with hßigh3 overexpression
Positive_regulation (overexpression) of Gene_expression (overexpression) of igh3 in eyes
2) Confidence 0.02 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2185514 Disease Relevance 0.93 Pain Relevance 0
At the age of two months, when plasma could safely be collected, the level of hßigh3 was measured in all wild-type and transgenic mice to establish hßigh3 overexpression in plasma.
Positive_regulation (overexpression) of Gene_expression (overexpression) of igh3 in plasma associated with targeted disruption
3) Confidence 0.02 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2185514 Disease Relevance 0.89 Pain Relevance 0
Transgenic mice overexpressing normal hßigh3 in the liver and blood
Positive_regulation (overexpressing) of Gene_expression (overexpressing) of igh3 in blood associated with targeted disruption
4) Confidence 0.02 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2185514 Disease Relevance 0.38 Pain Relevance 0
Transgenic mice overexpressing normal hßigh3 in the liver and blood
Positive_regulation (overexpressing) of in liver Gene_expression (overexpressing) of igh3 in blood associated with targeted disruption
5) Confidence 0.01 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2185514 Disease Relevance 0.38 Pain Relevance 0

General Comments

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