INT21925

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.37
First Reported 1990
Last Reported 2006
Negated 1
Speculated 1
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 0.64
Pain Relevance 0.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (PLB1) plasma membrane (PLB1)
Anatomy Link Frequency
endothelial cells 1
lip 1
heart 1
PLB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
interstitial cystitis 2 98.92 Very High Very High Very High
lidocaine 6 98.68 Very High Very High Very High
Inflammation 2 97.24 Very High Very High Very High
Inflammatory mediators 2 92.36 High High
palliative 33 50.00 Quite Low
Morphine 38 5.00 Very Low Very Low Very Low
Opioid 37 5.00 Very Low Very Low Very Low
tolerance 11 5.00 Very Low Very Low Very Low
depression 9 5.00 Very Low Very Low Very Low
sSRI 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Interstitial Cystitis 2 98.92 Very High Very High Very High
Dyspnea 137 98.64 Very High Very High Very High
INFLAMMATION 4 97.24 Very High Very High Very High
Pulmonary Disease 84 95.60 Very High Very High Very High
Anxiety Disorder 22 45.28 Quite Low
Shock 1 37.12 Quite Low
Panic Disorder 2 32.96 Quite Low
Cancer 3 26.24 Quite Low
Disease Progression 1 14.44 Low Low
Lung Cancer 19 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We examined the effect of multiple phospholipase A2 and cyclooxygenase inhibitors on the immediate release of prostacyclin from human bladder microvascular endothelial cells.
Spec (examined) Regulation (effect) of phospholipase A2 in endothelial cells
1) Confidence 0.37 Published 2006 Journal J. Urol. Section Abstract Doc Link 16952710 Disease Relevance 0.29 Pain Relevance 0.19
CONCLUSIONS: These results show that the search for a suitable anti-inflammatory agent that selectively target specific phospholipase A2 isoforms requires rigorous testing in several cell types in response to various stimuli.


Regulation (target) of phospholipase A2
2) Confidence 0.22 Published 2006 Journal J. Urol. Section Body Doc Link 16952710 Disease Relevance 0 Pain Relevance 0
Several controlled breathing techniques including positioning and pursed lip breathing (PLB) are useful in the management of breathlessness.
Regulation (controlled) of PLB in lip associated with dyspnea
3) Confidence 0.12 Published 2006 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2707160 Disease Relevance 0.35 Pain Relevance 0
When the heart was perfused with 0.5 mg methyl lidocaine/mL, acyltransferase activities were attenuated, but there was no change in the activities of phospholipase A or lysophospholipase.
Neg (no) Regulation (change) of lysophospholipase in heart associated with lidocaine
4) Confidence 0.03 Published 1990 Journal Biochem. Cell Biol. Section Abstract Doc Link 2222999 Disease Relevance 0 Pain Relevance 0.51

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox