INT219291

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Context Info
Confidence 0.39
First Reported 2007
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Kcnc1) transmembrane transport (Kcnc1)
Anatomy Link Frequency
myometrium 4
Kcnc1 (Mus musculus)
Pain Link Frequency Relevance Heat
potassium channel 8 94.00 High High
Pyramidal cell 8 91.80 High High
Hippocampus 5 91.52 High High
Action potential 6 26.28 Quite Low
Potency 4 16.96 Low Low
agonist 10 5.00 Very Low Very Low Very Low
tetrodotoxin 4 5.00 Very Low Very Low Very Low
sodium channel 2 5.00 Very Low Very Low Very Low
Dismenorea 2 5.00 Very Low Very Low Very Low
Calcium channel 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 4 5.00 Very Low Very Low Very Low
Sprains And Strains 3 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Dysmenorrhea 2 5.00 Very Low Very Low Very Low
Dislocations 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Epilepsy 1 5.00 Very Low Very Low Very Low
Adhesions 1 5.00 Very Low Very Low Very Low
Motor Neuron Diseases 1 5.00 Very Low Very Low Very Low
Autism 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, while Kv4.3 was expressed at relatively high levels in nonpregnant myometrium, we were essentially unable to detect this protein by Western blot in myometrial samples from term-pregnant mice (Figure 5, bottom panel).


Positive_regulation (levels) of Gene_expression (expressed) of Kv4 in myometrium
1) Confidence 0.39 Published 2007 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2186335 Disease Relevance 0 Pain Relevance 0
While our preparations are highly enriched for uterine smooth muscle, we cannot rule out a minor contribution by nervous or vascular tissues to our findings of Kv channel ?
Spec (findings) Positive_regulation (findings) of Gene_expression (channel) of Kv in uterine smooth muscle
2) Confidence 0.37 Published 2007 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2186335 Disease Relevance 0 Pain Relevance 0.05
Coexpression of DPP6 and Kv4.3 proteins
Positive_regulation (proteins) of Gene_expression (Coexpression) of Kv4
3) Confidence 0.34 Published 2008 Journal Frontiers in Molecular Neuroscience Section Body Doc Link PMC2576564 Disease Relevance 0 Pain Relevance 0.21

General Comments

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