INT219352

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Context Info
Confidence 0.22
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.72
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (CDK5, PAK1) cytosol (CDK5, PAK1) plasma membrane (CDK5, PAK1)
Golgi apparatus (PAK1) embryo development (CDK5) cell proliferation (CDK5)
Anatomy Link Frequency
neuron 1
CDK5 (Homo sapiens)
PAK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 2 54.16 Quite High
metalloproteinase 4 14.72 Low Low
ischemia 3 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 2 90.48 High High
Cv General 4 Under Development 3 80.32 Quite High
Stroke 53 79.12 Quite High
Cv Unclassified Under Development 9 66.44 Quite High
Middle Cerebral Artery Infarction 25 62.88 Quite High
INFLAMMATION 2 54.16 Quite High
Apoptosis 5 53.60 Quite High
Breast Cancer 1 32.88 Quite Low
Pathologic Processes 1 22.72 Low Low
Wound Healing 1 20.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Based on this evidence, these authors proposed the existence of a neuron-specific signalling complex involving Cdk5/p35-PAK1 that inhibits PAK1 activity in neurons.
Cdk5 Negative_regulation (inhibits) of PAK1 in neuron
1) Confidence 0.22 Published 2007 Journal BMC Neurosci Section Body Doc Link PMC2194693 Disease Relevance 0.72 Pain Relevance 0.03

General Comments

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