INT219506

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Context Info
Confidence 0.26
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (ARNT, AHR) signal transducer activity (ARNT, AHR) nucleus (ARNT, AHR)
transcription factor binding (ARNT, AHR) isomerase activity (Ppib) cell differentiation (ARNT)
ARNT (Homo sapiens)
AHR (Homo sapiens)
Ppib (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 3 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Dismenorea 1 5.00 Very Low Very Low Very Low
Dopamine 1 5.00 Very Low Very Low Very Low
Rheumatism 1 5.00 Very Low Very Low Very Low
nud 1 5.00 Very Low Very Low Very Low
Serotonin 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Breast Cancer 11 50.00 Quite Low
Apoptosis 30 46.08 Quite Low
Hepatocellular Cancer 1 29.60 Quite Low
Stress 30 22.08 Low Low
Cancer 7 15.60 Low Low
Hypoxia 17 5.00 Very Low Very Low Very Low
Adenocarcinoma 3 5.00 Very Low Very Low Very Low
Metastasis 2 5.00 Very Low Very Low Very Low
Hyperplasia 2 5.00 Very Low Very Low Very Low
Starvation 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The AhR, upon binding of a ligand, forms a heterodimeric complex with ARNT (aryl hydrocarbon receptor nuclear translocator) which induces transactivation of the CYPs and other target genes via binding to xenobiotic response elements (XREs) in their promoter regions [63].
ARNT Positive_regulation (induces) of AhR Binding (binding) of CYPs
1) Confidence 0.26 Published 2007 Journal BMC Pharmacol Section Body Doc Link PMC2194763 Disease Relevance 0 Pain Relevance 0

General Comments

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