INT219686

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Context Info
Confidence 0.12
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 11.35
Pain Relevance 1.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CEL) extracellular space (CEL) small molecule metabolic process (CEL)
extracellular region (CEL) lipid metabolic process (CEL) cytoplasm (CEL)
Anatomy Link Frequency
macrophages 4
CEL (Homo sapiens)
COPD (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 284 100.00 Very High Very High Very High
Inflammation 128 98.48 Very High Very High Very High
Inflammatory response 12 65.00 Quite High
lidocaine 4 5.00 Very Low Very Low Very Low
agonist 4 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nicotine Addiction 692 100.00 Very High Very High Very High
Pulmonary Disease 424 100.00 Very High Very High Very High
INFLAMMATION 140 98.48 Very High Very High Very High
Disease 16 90.28 High High
Emphysema 24 74.64 Quite High
Lower Respiratory Tract Infection 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, the pack-years correlated with BAL macrophages in COPD smokers (R = 0.87, p < 0.05) and 'healthy' smokers (R = 0.68, p < 0.05).
BAL Binding (macrophages) of COPD in macrophages associated with nicotine addiction and pulmonary disease
1) Confidence 0.12 Published 2007 Journal Respir Res Section Body Doc Link PMC2200652 Disease Relevance 2.64 Pain Relevance 0.27
Also, the similar amount of BAL macrophages in COPD ex-smokers, 'healthy' smokers and never-smokers, suggests the possibility of positive alterations in the alveolar compartment after smoking cessation.
BAL Binding (macrophages) of COPD in macrophages associated with nicotine addiction and pulmonary disease
2) Confidence 0.12 Published 2007 Journal Respir Res Section Body Doc Link PMC2200652 Disease Relevance 3.12 Pain Relevance 0.24
Furthermore, the number of BAL MMP-12+-macrophages was higher in COPD smokers compared to COPD ex-smokers, and in 'healthy' smokers compared to healthy never-smokers (Fig. 3).
BAL Binding (number) of COPD in macrophages associated with nicotine addiction, pulmonary disease and metalloproteinase
3) Confidence 0.12 Published 2007 Journal Respir Res Section Body Doc Link PMC2200652 Disease Relevance 2.80 Pain Relevance 0.37
Furthermore, the number of BAL MMP-12+-macrophages was higher in COPD smokers compared to COPD ex-smokers, and in 'healthy' smokers compared to healthy never-smokers (Fig. 3).
BAL Binding (number) of COPD in macrophages associated with nicotine addiction, pulmonary disease and metalloproteinase
4) Confidence 0.12 Published 2007 Journal Respir Res Section Body Doc Link PMC2200652 Disease Relevance 2.79 Pain Relevance 0.37

General Comments

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