INT219714

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.49
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
bone marrow 1
l5H1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 21 100.00 Very High Very High Very High
chemokine 1 100.00 Very High Very High Very High
Inflammation 1 88.00 High High
addiction 1 57.56 Quite High
ketamine 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 40 100.00 Very High Very High Very High
Immunization 68 98.80 Very High Very High Very High
Fever 1 98.52 Very High Very High Very High
Disease 14 96.40 Very High Very High Very High
Influenza Virus Infection 190 89.28 High High
INFLAMMATION 1 88.00 High High
Sprains And Strains 14 52.68 Quite High
Papillomavirus Infection 2 29.48 Quite Low
Influenza In Birds 20 18.92 Low Low
Death 7 14.64 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Significant numbers of virus-specific antibody secreting bone marrow cells were noted from H5N1 VLP-immunized mice but not from PBS control mice within 18 hr in culture, suggesting that pre-existing plasma cells induced by VLP vaccination were actively secreting antibodies to H5N1 virus antigen (Fig. 7A).
Localization (secreting) of H5N1 in bone marrow
1) Confidence 0.03 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2646145 Disease Relevance 0.23 Pain Relevance 0
secreting splenocytes upon the stimulation with an H5 HA specific peptide pool derived from A/Thailand/16/04 (accession number APB51982, H5N1) which has over 99% homology to VN/04 HA (Fig. 9).
Localization (secreting) of H5N1
2) Confidence 0.01 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2646145 Disease Relevance 0.24 Pain Relevance 0.05
H5N1 infection in humans activates cytokine/chemokine secretion resulting in the occurrence of a “cytokine storm” that may contribute to the severity of disease by these viruses [53]–[56].
Localization (secretion) of H5N1 associated with chemokine, disease, infection and cytokine
3) Confidence 0.01 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2200794 Disease Relevance 1.02 Pain Relevance 0.31

General Comments

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