INT219766

Context Info Confidence 0.36 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 3 Disease Relevance 1.83 Pain Relevance 0

nucleolus (Wasl) cytoskeleton (Wasl) nucleus (Wasl) protein complex assembly (Wasl) cytoplasm (Wasl)

Anatomy Link Frequency platelets 1 band 1 Wasl (Mus musculus)

Pain Link Frequency Relevance Heat agonist 18 5.00 Analgesic 3 5.00 Buprenorphine 3 5.00

Disease Link Frequency Relevance Heat Cicatrix 18 97.44 Thrombosis 15 96.88 Stress 3 30.04 Hemorrhage 15 5.00 Targeted Disruption 6 5.00 Adhesions 6 5.00 Coagulation Disorder 3 5.00 Injury 3 5.00 Apoptosis 3 5.00 Disseminated Intravascular Coagulation 3 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

No band was observed on these blots indicating that N-WASp, if present in platelets, is expressed at low levels (below the detection limit of this antibody on western blot) and that a lack of a HS1-/- phenotype is not due to an increase in N-WASp expression.

Gene_expression (expressed) of N-WASp in band

1) Confidence 0.36 Published 2007 Journal BMC Cell Biol Section Body Doc Link PMC2203996 Disease Relevance 0.62 Pain Relevance 0

No band was observed on these blots indicating that N-WASp, if present in platelets, is expressed at low levels (below the detection limit of this antibody on western blot) and that a lack of a HS1-/- phenotype is not due to an increase in N-WASp expression.

Gene_expression (expression) of N-WASp in platelets

2) Confidence 0.31 Published 2007 Journal BMC Cell Biol Section Body Doc Link PMC2203996 Disease Relevance 0.60 Pain Relevance 0

Western blots were also probed for N-WASp.

Gene_expression (probed) of N-WASp

3) Confidence 0.27 Published 2007 Journal BMC Cell Biol Section Body Doc Link PMC2203996 Disease Relevance 0.62 Pain Relevance 0

General Comments

This test has worked.