INT219879

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Context Info
Confidence 0.30
First Reported 2007
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 7.64
Pain Relevance 1.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (SPINK5) extracellular region (SPINK5) endoplasmic reticulum (SPINK5)
extracellular matrix organization (SPINK5) cytoplasm (SPINK5)
SPINK5 (Homo sapiens)
Pain Link Frequency Relevance Heat
Somatostatin 124 99.08 Very High Very High Very High
abdominal pain 17 88.48 High High
ischemia 3 86.48 High High
agonist 3 83.68 Quite High
imagery 84 82.36 Quite High
Serotonin 8 81.16 Quite High
positron emission tomography 21 74.92 Quite High
Bile 3 56.08 Quite High
Pain 4 49.68 Quite Low
Catecholamine 3 39.08 Quite Low
Disease Link Frequency Relevance Heat
Neuroendocrine Cancer 68 100.00 Very High Very High Very High
Endocrine Gland Neoplasms 2 98.64 Very High Very High Very High
Syndrome 59 97.96 Very High Very High Very High
Disease 45 97.80 Very High Very High Very High
Metastasis 60 97.12 Very High Very High Very High
Watson Syndrome 1 96.68 Very High Very High Very High
Cancer 211 96.36 Very High Very High Very High
Pancreatic Cancer 10 96.00 Very High Very High Very High
Von Hippel-lindau Syndrome 2 95.16 Very High Very High Very High
Liver Cancer 3 92.44 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Pancreatic NETs
Positive_regulation (Pancreatic) of NETs
1) Confidence 0.30 Published 2007 Journal Pediatr Radiol Section Body Doc Link PMC2292492 Disease Relevance 1.92 Pain Relevance 0.22
Appendiceal NETs
Positive_regulation (Appendiceal) of NETs
2) Confidence 0.30 Published 2007 Journal Pediatr Radiol Section Body Doc Link PMC2292492 Disease Relevance 1.14 Pain Relevance 0.19
Hepatic NETs
Positive_regulation (Hepatic) of NETs
3) Confidence 0.30 Published 2007 Journal Pediatr Radiol Section Body Doc Link PMC2292492 Disease Relevance 1.49 Pain Relevance 0.25
The initial treatment of GEP NETs is, where possible, always an aggressive surgical approach, aimed at obtaining a curative tumour ablation, even in the presence of metastatic disease.
Positive_regulation (treatment) of NETs associated with cancer and metastasis
4) Confidence 0.20 Published 2010 Journal J Exp Clin Cancer Res Section Body Doc Link PMC2845555 Disease Relevance 0.41 Pain Relevance 0.40
Though the majority of NETs occur spontaneously, NETs may occur also as part of complex familial endocrine cancer syndromes such as MEN-1, MEN-2, Neurofibromatosis type 1(NFT type 1), Von Hippel Lindau disease, and Carney's Complex [9-11].
Spec (may) Positive_regulation (occur) of NETs associated with endocrine gland neoplasms, neuroendocrine cancer, syndrome, von hippel-lindau syndrome, disease and watson syndrome
5) Confidence 0.14 Published 2007 Journal J Med Case Reports Section Body Doc Link PMC2204028 Disease Relevance 2.68 Pain Relevance 0.09

General Comments

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