INT219915

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Context Info
Confidence 0.33
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Trpv1) extracellular space (Edn1) extracellular region (Edn1)
plasma membrane (Trpv1) lipid metabolic process (Trpv1) cell-cell signaling (Edn1)
Edn1 (Rattus norvegicus)
Trpv1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
qutenza 40 87.52 High High
ASIC 1 83.16 Quite High
dorsal root ganglion 22 5.00 Very Low Very Low Very Low
bradykinin 10 5.00 Very Low Very Low Very Low
nociceptor 6 5.00 Very Low Very Low Very Low
Pain 5 5.00 Very Low Very Low Very Low
agonist 5 5.00 Very Low Very Low Very Low
algogenic 4 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
tetrodotoxin 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 23 5.00 Very Low Very Low Very Low
Nociception 7 5.00 Very Low Very Low Very Low
Hyperalgesia 5 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Neuropathic Pain 4 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Reprotox - General 1 1 5.00 Very Low Very Low Very Low
Cancer 1 5.00 Very Low Very Low Very Low
Inflammatory Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
ET-1 augmented the responses to the increase in temperature (2.5 ± 0.6-fold, n = 10, for the first response after ET-1, Fig. 3I) and, as illustrated for the experiment in Fig.3G, 3H, shifted the threshold for TRPV1 activation to lower temperatures (Fig. 3J).
ET-1 Regulation (threshold) of Positive_regulation (activation) of TRPV1
1) Confidence 0.33 Published 2007 Journal Mol Pain Section Body Doc Link PMC2206006 Disease Relevance 0 Pain Relevance 0.18

General Comments

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