INT220043

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Context Info
Confidence 0.41
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.94
Pain Relevance 0.83

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Ido1) oxidoreductase activity (Ido1) cytoplasm (Ido1)
Ido1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 24 97.28 Very High Very High Very High
Arthritis 61 96.80 Very High Very High Very High
Multiple sclerosis 62 89.84 High High
Demyelination 12 82.88 Quite High
cytokine 10 74.96 Quite High
rheumatoid arthritis 18 74.80 Quite High
agonist 2 65.68 Quite High
abatacept 1 58.00 Quite High
tolerance 2 36.52 Quite Low
dexamethasone 2 33.76 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 27 97.28 Very High Very High Very High
Arthritis 67 96.80 Very High Very High Very High
Necrosis 3 94.96 High High
Cancer 5 94.60 High High
Multiple Sclerosis 35 91.92 High High
Demyelinating Disease 84 89.84 High High
Apoptosis 1 77.40 Quite High
Rheumatoid Arthritis 18 74.80 Quite High
Autoimmune Disease 9 46.56 Quite Low
Arthropathy 4 33.04 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results showed that treatment of mice with the anti-CD137 antibody resulted in induction of IDO in vivo, which was associated with significant amelioration of the severity of CIA [26].
Positive_regulation (resulted) of Positive_regulation (induction) of IDO associated with arthritis
1) Confidence 0.41 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2206348 Disease Relevance 0.92 Pain Relevance 0.38
Most

significantly the induction IDO activity is required for the full

Positive_regulation (required) of Positive_regulation (induction) of IDO
2) Confidence 0.21 Published 2009 Journal PPAR Research Section Body Doc Link PMC2683338 Disease Relevance 1.02 Pain Relevance 0.45

General Comments

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