INT220050

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Context Info
Confidence 0.31
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.45
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Ido1) oxidoreductase activity (Ido1) Golgi apparatus (Ctla4)
plasma membrane (Ctla4) cytoplasm (Ido1)
Anatomy Link Frequency
cytotoxic T lymphocyte 2
Ctla4 (Mus musculus)
Ido1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 36 75.76 Quite High
tolerance 4 65.48 Quite High
Inflammatory response 6 64.08 Quite High
metalloproteinase 4 61.92 Quite High
Arthritis 120 50.00 Quite Low
cytokine 14 16.32 Low Low
rheumatoid arthritis 28 15.60 Low Low
abatacept 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 4 95.04 Very High Very High Very High
Cancer 8 84.28 Quite High
Organ Transplantation 2 77.36 Quite High
Autoimmune Disease 4 76.44 Quite High
INFLAMMATION 42 75.76 Quite High
Starvation 8 75.60 Quite High
Arthritis 130 50.00 Quite Low
Rheumatoid Arthritis 28 15.60 Low Low
Sprains And Strains 2 13.52 Low Low
Immunization 16 12.64 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
, IL-10, and cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) have also been shown to stimulate IDO [4,6].
CTLA-4 Positive_regulation (stimulate) of IDO in cytotoxic T lymphocyte
1) Confidence 0.31 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2206348 Disease Relevance 0.72 Pain Relevance 0.19
, IL-10, and cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) have also been shown to stimulate IDO [4,6].
lymphocyte-associated antigen-4 Positive_regulation (stimulate) of IDO in cytotoxic T lymphocyte
2) Confidence 0.27 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2206348 Disease Relevance 0.73 Pain Relevance 0.19

General Comments

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