INT220051

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.24
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Ido1) oxidoreductase activity (Ido1) cytoplasm (Ido1)
Fcgr4 (Mus musculus)
Ido1 (Mus musculus)
Pain Link Frequency Relevance Heat
abatacept 1 99.96 Very High Very High Very High
Arthritis 60 94.72 High High
rheumatoid arthritis 14 91.24 High High
Inflammation 18 83.44 Quite High
tolerance 2 13.96 Low Low
cytokine 7 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Arthritis 65 94.72 High High
Rheumatoid Arthritis 14 91.24 High High
INFLAMMATION 21 83.44 Quite High
Arthropathy 4 82.40 Quite High
Necrosis 2 72.40 Quite High
Cancer 4 72.04 Quite High
Apoptosis 1 54.84 Quite High
Immunization 8 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 7 5.00 Very Low Very Low Very Low
Erythema 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, abatacept (CTLA4-Ig) therapy may act, at least in part, by the stimulation of IDO production.


CTLA4-Ig Positive_regulation (stimulation) of Gene_expression (production) of IDO associated with abatacept
1) Confidence 0.01 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2206348 Disease Relevance 1.24 Pain Relevance 0.55

General Comments

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