INT220078

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Context Info
Confidence 0.13
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 5.03
Pain Relevance 3.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (KNG1) extracellular region (KNG1) plasma membrane (KNG1)
Anatomy Link Frequency
lung 4
KNG1 (Homo sapiens)
Pain Link Frequency Relevance Heat
bradykinin 12 100.00 Very High Very High Very High
Central nervous system 38 97.36 Very High Very High Very High
nociceptor 10 97.36 Very High Very High Very High
IPN 14 96.60 Very High Very High Very High
analgesia 24 93.16 High High
agonist 24 89.56 High High
opioid receptor 26 89.20 High High
Inflammation 64 82.20 Quite High
Lasting pain 44 80.64 Quite High
Acute pain 4 77.80 Quite High
Disease Link Frequency Relevance Heat
Weight Loss 86 100.00 Very High Very High Very High
Asthma 166 97.44 Very High Very High Very High
Inflammatory Pain 14 96.60 Very High Very High Very High
Obesity 88 94.52 High High
Occupational Lung Diseases 2 89.92 High High
INFLAMMATION 80 82.20 Quite High
Pain 236 80.64 Quite High
Injury 22 79.20 Quite High
Cardiovascular Disease 4 74.40 Quite High
Hypertension 2 60.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The abundant metabolite of bradykinin, des-Arg9-bradykinin (kallidin), activates B1 receptors, which occur in low abundance, in the periphery and CNS [19-21].
Positive_regulation (activates) of Negative_regulation (metabolite) of bradykinin associated with central nervous system and bradykinin
1) Confidence 0.13 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2206352 Disease Relevance 0.74 Pain Relevance 1.71
The abundant metabolite of bradykinin, des-Arg9-bradykinin (kallidin), activates B1 receptors, which occur in low abundance, in the periphery and CNS [19-21].
Positive_regulation (activates) of Negative_regulation (metabolite) of des-Arg9-bradykinin associated with central nervous system and bradykinin
2) Confidence 0.12 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2206352 Disease Relevance 0.74 Pain Relevance 1.71
The evidence available to date suggests that weight loss, induced by surgery or caloric restriction, is associated with improved asthma symptoms, lung function, medication usage, and quality of life in obese adults with asthma [23-26].
Positive_regulation (induced) of Negative_regulation (loss) of weight in lung associated with asthma, weight loss and obesity
3) Confidence 0.02 Published 2010 Journal BMC Pulm Med Section Body Doc Link PMC2860346 Disease Relevance 1.66 Pain Relevance 0
Other, non-randomized studies reported that weight loss induced by surgery [70-72] or dietary restriction [23,24,26,73] was associated with improved asthma symptoms, lung function, medication use, quality of life, and health care utilization.
Positive_regulation (induced) of Negative_regulation (loss) of weight in lung associated with asthma and weight loss
4) Confidence 0.02 Published 2010 Journal BMC Pulm Med Section Body Doc Link PMC2860346 Disease Relevance 1.89 Pain Relevance 0

General Comments

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