INT220116

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Context Info
Confidence 0.06
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.56
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tnfrsf1a, TNF) extracellular space (Tnfrsf1a, TNF) extracellular region (Tnfrsf1a, TNF)
plasma membrane (Tnfrsf1a, TNF) intracellular (TNF) nucleus (Tnfrsf1a)
Tnfrsf1a (Mus musculus)
TNF (Homo sapiens)
Pain Link Frequency Relevance Heat
Etanercept 2 98.76 Very High Very High Very High
cytokine 7 89.12 High High
Arthritis 2 49.04 Quite Low
Inflammation 23 36.80 Quite Low
rheumatoid arthritis 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Tumor Necrosis Factor Receptor-associated Periodic Syndrome 65 97.96 Very High Very High Very High
Targeted Disruption 2 70.56 Quite High
Hepatitis 1 54.08 Quite High
Fever 23 50.00 Quite Low
Arthritis 2 49.04 Quite Low
INFLAMMATION 23 36.80 Quite Low
Disease 15 20.64 Low Low
Syndrome 13 5.00 Very Low Very Low Very Low
Apoptosis 7 5.00 Very Low Very Low Very Low
Stress 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Shed TNFR1 can function as a soluble inhibitor of TNF and forms the basis for using etanercept to treat TRAPS.
TNFR1 Negative_regulation (inhibitor) of TNF associated with tumor necrosis factor receptor-associated periodic syndrome and etanercept
1) Confidence 0.06 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2206363 Disease Relevance 0.56 Pain Relevance 0.09

General Comments

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