INT220149

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Context Info
Confidence 0.39
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.44
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (IGF1, IGFALS) extracellular space (IGF1, IGFALS) extracellular region (IGF1, IGFALS)
cell adhesion (IGFALS) nucleolus (IGFALS) nucleus (IGFALS)
Anatomy Link Frequency
liver 1
IGF1 (Homo sapiens)
IGFALS (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 77 79.92 Quite High
cytokine 16 5.00 Very Low Very Low Very Low
Inflammation 11 5.00 Very Low Very Low Very Low
methotrexate 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Inflammatory marker 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Acupuncture 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 10 88.88 High High
Rheumatoid Arthritis 77 79.92 Quite High
Obesity 20 47.84 Quite Low
Disorder Of Lipid Metabolism 4 39.96 Quite Low
Laron Syndrome 15 5.00 Very Low Very Low Very Low
Hypoglycemia 14 5.00 Very Low Very Low Very Low
INFLAMMATION 13 5.00 Very Low Very Low Very Low
Appetite Loss 8 5.00 Very Low Very Low Very Low
Syndrome 6 5.00 Very Low Very Low Very Low
Cancer 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is worth noting that IGF-1 usually complexes with IGFBP-3 and ALS that depend on GH level and action.
IGF-1 Binding (complexes) of ALS
1) Confidence 0.39 Published 2009 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2724186 Disease Relevance 0 Pain Relevance 0
IGF-I circulates as a ternary complex with IGFBP-3 and the acid-labile subunit, and both liver-derived proteins are under the control of GH [20].
IGF-I Binding (complex) of acid-labile subunit in liver
2) Confidence 0.00 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2206381 Disease Relevance 0.44 Pain Relevance 0.10

General Comments

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