INT220240

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (IL1RN, MOCS1) small molecule metabolic process (MOCS1) intracellular (IL1RN)
cytoplasm (IL1RN) cytosol (MOCS1) extracellular space (IL1RN)
IL1RN (Homo sapiens)
MOCS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 24 93.52 High High
antagonist 12 50.00 Quite Low
Sciatica 21 5.00 Very Low Very Low Very Low
cytokine 15 5.00 Very Low Very Low Very Low
Chronic low back pain 6 5.00 Very Low Very Low Very Low
backache 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nerve Root Compression 21 5.00 Very Low Very Low Very Low
Low Back Pain 12 5.00 Very Low Very Low Very Low
Disease 12 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 9 5.00 Very Low Very Low Very Low
Musculoskeletal Disease 3 5.00 Very Low Very Low Very Low
Apoptosis 3 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low
Cadaver 3 5.00 Very Low Very Low Very Low
Arthropathy 3 5.00 Very Low Very Low Very Low
Infection 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
increased and IL-1Ra decreased enzyme expression in a similar pattern to that in moderately degenerate IVDs.


IL-1Ra Negative_regulation (decreased) of Gene_expression (expression) of enzyme
1) Confidence 0.01 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2206387 Disease Relevance 0 Pain Relevance 0.03
In AF and NP, IL-1Ra reduced enzyme expression by at least 90% (p < 0.01).


IL-1Ra Negative_regulation (reduced) of Gene_expression (expression) of enzyme
2) Confidence 0.01 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2206387 Disease Relevance 0 Pain Relevance 0.04
IL-1Ra reduced immunodetectable enzyme expression by at least 90% for all enzymes in AF and NP (p < 0.02).


IL-1Ra Negative_regulation (reduced) of Gene_expression (expression) of enzyme
3) Confidence 0.01 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2206387 Disease Relevance 0 Pain Relevance 0.05

General Comments

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