INT220261

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.35
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (MOCS1) small molecule metabolic process (MOCS1) nucleus (MOCS1)
MOCS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Catechol-O-methyltransferase 109 80.16 Quite High
antagonist 4 50.00 Quite Low
Catecholamine 7 48.24 Quite Low
Sciatica 7 41.68 Quite Low
backache 2 38.64 Quite Low
Pain 19 5.00 Very Low Very Low Very Low
metalloproteinase 8 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
Dopamine 3 5.00 Very Low Very Low Very Low
Chronic low back pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hantavirus Infection 78 83.44 Quite High
Disease 6 69.68 Quite High
Nerve Root Compression 7 41.68 Quite Low
Low Back Pain 4 38.64 Quite Low
Pain 19 5.00 Very Low Very Low Very Low
Cognitive Disorder 7 5.00 Very Low Very Low Very Low
Schizophrenia 5 5.00 Very Low Very Low Very Low
Temporomandibular Joint Disorders 5 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 3 5.00 Very Low Very Low Very Low
Anxiety Disorder 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, it inhibited enzyme expression when EDTA did not, suggesting IL-1 would be a better clinical target than MDP in the management of DIVD.
Negative_regulation (inhibited) of Gene_expression (expression) of enzyme
1) Confidence 0.01 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2206387 Disease Relevance 0.07 Pain Relevance 0
Thus, minor SNPs linked to the APS haplotype may compensate for the decreased enzyme thermostability produced by the met158 allele.
Negative_regulation (decreased) of Gene_expression (produced) of enzyme
2) Confidence 0.01 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2664927 Disease Relevance 0.28 Pain Relevance 0.26

General Comments

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