INT220316

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.10
First Reported 2007
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 4
Total Number 6
Disease Relevance 5.71
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
plasma 1
epithelium 1
Aliq1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory mediators 2 90.20 High High
Inflammatory response 16 89.12 High High
cytokine 16 87.60 High High
Inflammation 49 81.00 Quite High
cva 7 67.68 Quite High
Arthritis 2 64.24 Quite High
Paracetamol 4 52.04 Quite High
ischemia 8 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
agonist 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adult Respiratory Distress Syndrome 262 100.00 Very High Very High Very High
Targeted Disruption 1 98.90 Very High Very High Very High
Systemic Inflammatory Response Syndrome 12 97.20 Very High Very High Very High
Hemorrhagic Shock 64 95.24 Very High Very High Very High
Lung Injury 48 93.20 High High
Injury 74 92.20 High High
Infection 5 91.48 High High
INFLAMMATION 52 89.80 High High
Body Weight 4 78.36 Quite High
Death 9 76.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our immuno-histochemical studies showed that NEP was expressed in the alveolar wall, most prominently in type II alveolar epithelium, and that this expression was decreased by the epithelial sloughing associated with ALI.
ALI Binding (associated) of in epithelium associated with adult respiratory distress syndrome
1) Confidence 0.10 Published 2010 Journal Respir Res Section Body Doc Link PMC3009633 Disease Relevance 0.99 Pain Relevance 0.09
NEP activity in plasma of patients with ALI/ARDS
ALI/ARDS Binding (plasma) of in plasma associated with adult respiratory distress syndrome
2) Confidence 0.10 Published 2010 Journal Respir Res Section Body Doc Link PMC3009633 Disease Relevance 0.54 Pain Relevance 0
As stated above, the prone position improves oxygenation in most patients with ALI/ARDS but may or may not improve outcomes [35,36].
ALI Binding (oxygenation) of associated with adult respiratory distress syndrome
3) Confidence 0.07 Published 2007 Journal Crit Care Section Body Doc Link PMC2206500 Disease Relevance 0.84 Pain Relevance 0.10
The study using MT-I/II knock out mice has demonstrated that endogenous MT protects against ALI induced by LPS possibly via a protective effect on the vascular integrity, but not through inhibition of the NF-?
ALI Binding (against) of associated with targeted disruption and adult respiratory distress syndrome
4) Confidence 0.06 Published 2010 Journal Journal of Clinical Biochemistry and Nutrition Section Body Doc Link PMC2872229 Disease Relevance 0.33 Pain Relevance 0.04
Therefore, antioxidant strategies together with modification of TLR pathways are likely to be a logical therapeutic target for ALI.



ALI Spec (likely) Binding (target) of associated with adult respiratory distress syndrome
5) Confidence 0.02 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2913855 Disease Relevance 0.87 Pain Relevance 0.09
Over the past decade, despite improvements in supportive care, ALI is still associated with a high mortality rate ranging from 26 to 35 percent [9].
ALI Binding (associated) of associated with adult respiratory distress syndrome
6) Confidence 0.02 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2913855 Disease Relevance 2.15 Pain Relevance 0.28

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox