INT22032

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Context Info
Confidence 0.41
First Reported 1983
Last Reported 2008
Negated 1
Speculated 1
Reported most in Abstract
Documents 4
Total Number 5
Disease Relevance 0.82
Pain Relevance 0.81

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (CEBPZ) DNA binding (CEBPZ)
Anatomy Link Frequency
spikes 4
blood 2
CEBPZ (Homo sapiens)
Pain Link Frequency Relevance Heat
anesthesia 16 91.28 High High
Hippocampus 15 89.68 High High
imagery 25 75.12 Quite High
positron emission tomography 18 64.52 Quite High
isoflurane 4 57.84 Quite High
halothane 2 50.00 Quite Low
amygdala 49 37.56 Quite Low
Anterior cingulate 6 36.32 Quite Low
Anterior cingulate cortex 21 26.60 Quite Low
insula 19 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Dyspnea 2 100.00 Very High Very High Very High
Cerebrovascular Disease 1 98.20 Very High Very High Very High
Panic Disorder 36 97.28 Very High Very High Very High
Anxiety Disorder 107 61.24 Quite High
Increased Venous Pressure Under Development 2 56.04 Quite High
Urological Neuroanatomy 12 40.16 Quite Low
Phobia 59 5.00 Very Low Very Low Very Low
Generalized Anxiety Disorder 9 5.00 Very Low Very Low Very Low
Cognitive Disorder 8 5.00 Very Low Very Low Very Low
Agoraphobia 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
All three examined volatile anesthetics significantly (P<0.01) increased CBF equivalent in a dose-dependent manner (0.5, 1.0, 1.5 MAC).
Positive_regulation (increased) of Negative_regulation (equivalent) of CBF
1) Confidence 0.41 Published 1996 Journal Anesthesiology Section Body Doc Link 8659783 Disease Relevance 0 Pain Relevance 0
This was not the case in patients who had panicked, but maybe because of induced hyperventilation decreasing CBF.
Neg (not) Positive_regulation (induced) of Neg (not) Negative_regulation (decreasing) of CBF associated with dyspnea
2) Confidence 0.38 Published 2008 Journal J Neural Transm Section Body Doc Link PMC2694920 Disease Relevance 0.73 Pain Relevance 0.15
Sudden decreases in cerebral perfusion pressure due to changes from a horizontal to a head-elevated position may cause decreases in cerebral blood flow (CBF), particularly in patients with preexisting cerebrovascular disease.
Spec (may) Positive_regulation (cause) of Negative_regulation (decreases) of CBF in blood associated with cerebrovascular disease
3) Confidence 0.35 Published 1990 Journal Anaesthesist Section Abstract Doc Link 2240563 Disease Relevance 0.10 Pain Relevance 0.28
The results indicate that enflurane is a cerebral vasodilator and causes an increase in CBF and a decrease in CMRO2 in humans at an anesthetic level characterized by frequent spikes and suppression on the EEG.
Positive_regulation (increase) of Negative_regulation (decrease) of CBF in spikes
4) Confidence 0.31 Published 1983 Journal Anesthesiology Section Abstract Doc Link 6650909 Disease Relevance 0 Pain Relevance 0.19
The results indicate that enflurane is a cerebral vasodilator and causes an increase in CBF and a decrease in CMRO2 in humans at an anesthetic level characterized by frequent spikes and suppression on the EEG.
Positive_regulation (causes) of Negative_regulation (decrease) of CBF in spikes
5) Confidence 0.31 Published 1983 Journal Anesthesiology Section Abstract Doc Link 6650909 Disease Relevance 0 Pain Relevance 0.19

General Comments

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