INT220365

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.45
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.28
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Igf1) extracellular region (Igf1)
Anatomy Link Frequency
hepatocytes 2
Igf1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
dexamethasone 45 99.98 Very High Very High Very High
cytokine 104 87.68 High High
Inflammation 4 87.28 High High
analgesia 4 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
Buprenorphine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Bronchopulmonary Dysplasia 10 93.80 High High
Sepsis 74 92.56 High High
INFLAMMATION 4 87.28 High High
Pulmonary Disease 3 67.80 Quite High
Weight Gain 3 45.36 Quite Low
Body Weight 18 41.60 Quite Low
Cleidocranial Dysplasia 3 21.92 Low Low
Critical Illness 18 5.00 Very Low Very Low Very Low
Starvation 10 5.00 Very Low Very Low Very Low
Ileus 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We now demonstrate continued induction of SOCS-3 expression at 72 hours after CLP, associated with reduced hepatic expression of mRNA of IGF-I and reduced serum IGF-I concentrations.
Negative_regulation (reduced) of Transcription (expression) of IGF-I
1) Confidence 0.45 Published 2007 Journal Crit Care Section Body Doc Link PMC2206515 Disease Relevance 0.52 Pain Relevance 0.11
We now demonstrate continued induction of SOCS-3 expression at 72 hours after CLP, associated with reduced hepatic expression of mRNA of IGF-I and reduced serum IGF-I concentrations.
Negative_regulation (reduced) of Transcription (expression) of serum IGF-I
2) Confidence 0.28 Published 2007 Journal Crit Care Section Body Doc Link PMC2206515 Disease Relevance 0.52 Pain Relevance 0.11
In human fibroblast dexamethasone blocks IGFBP-3, IGFBP-4 and IGFBP-5 mRNA transcription (Connover et al 1995), in hepatocytes IGF-I mRNA (El-Khattabi et al 2003).
Negative_regulation (blocks) of Transcription (transcription) of IGF-I in hepatocytes associated with dexamethasone
3) Confidence 0.03 Published 2007 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721283 Disease Relevance 0.24 Pain Relevance 0.33

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox