INT220374

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Context Info
Confidence 0.27
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.03
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Igfbp1) extracellular region (Igfbp1)
Igfbp1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
dexamethasone 45 99.98 Very High Very High Very High
cytokine 52 94.92 High High
anesthesia 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
analgesia 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Buprenorphine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sepsis 37 97.44 Very High Very High Very High
Hyperinsulinism 1 97.32 Very High Very High Very High
Hyperglycemia 1 96.28 Very High Very High Very High
Bronchopulmonary Dysplasia 10 85.44 High High
Critical Illness 9 76.20 Quite High
Metabolic Syndrome 1 71.76 Quite High
Cardiovascular Disease 2 69.92 Quite High
Weight Gain 3 62.32 Quite High
Infection 2 38.72 Quite Low
Intrauterine Growth Retardation 1 35.80 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Dexamethasone induces the hepatic synthesis of IGFBP-1.


Positive_regulation (induces) of Gene_expression (synthesis) of IGFBP-1 associated with dexamethasone
1) Confidence 0.27 Published 2007 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721283 Disease Relevance 0.56 Pain Relevance 0.20
Our observations that PN was more efficacious, in comparison with EN, in influencing circulating IGF-I and IGFBP-I levels are in contrast to another rodent study comparing PN and EN in sepsis [28].
Positive_regulation (circulating) of Gene_expression (levels) of IGFBP-I associated with sepsis
2) Confidence 0.20 Published 2007 Journal Crit Care Section Body Doc Link PMC2206515 Disease Relevance 0.47 Pain Relevance 0.17

General Comments

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