INT22041

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Context Info
Confidence 0.01
First Reported 1990
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 0.17
Pain Relevance 2.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
eyes 1
Gtpc (Mus musculus)
Pain Link Frequency Relevance Heat
adenocard 14 99.98 Very High Very High Very High
halothane 9 99.84 Very High Very High Very High
anesthesia 11 99.80 Very High Very High Very High
ketamine 8 97.84 Very High Very High Very High
agonist 1 96.76 Very High Very High Very High
isoflurane 17 95.28 Very High Very High Very High
nMDA receptor 5 88.00 High High
Glutamate receptor 1 80.24 Quite High
Analgesic 3 79.04 Quite High
antagonist 2 73.84 Quite High
Disease Link Frequency Relevance Heat
Hypotension 2 92.16 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Adenosine decreases the minimum alveolar concentration of halothane in dogs.
Negative_regulation (decreases) of concentration associated with adenocard and halothane
1) Confidence 0.01 Published 1990 Journal Anesthesiology Section Title Doc Link 2240689 Disease Relevance 0.17 Pain Relevance 1.06
We studied 49 patients of ASA physical status I to determine cerebral anesthetic concentration on awakening calculated with end-tidal anesthetic concentration, when the end-tidal concentration decreased spontaneously.
Negative_regulation (decreased) of concentration
2) Confidence 0.01 Published 1993 Journal Anesth. Analg. Section Abstract Doc Link 8214700 Disease Relevance 0 Pain Relevance 0.12
The authors conclude that awakening concentration decreases at the similar rate of decrease in minimum alveolar concentration (MAC) with increasing age; and therefore, the ratios to MAC are fairly constant, being 0.34 for both sevoflurane and isoflurane.
Negative_regulation (decrease) of concentration associated with isoflurane
3) Confidence 0.00 Published 1993 Journal Anesth. Analg. Section Abstract Doc Link 8424514 Disease Relevance 0 Pain Relevance 0.52
If patients failed to open their eyes on request, the end-tidal concentration was decreased and again maintained at a constant level for 15 min.
Negative_regulation (decreased) of concentration in eyes
4) Confidence 0.00 Published 1993 Journal Anesth. Analg. Section Abstract Doc Link 8424514 Disease Relevance 0 Pain Relevance 0.48
On both NR1/NR2A and NR1/NR2B receptors, 50% inhibitory concentration for volatile anesthetics was reduced approximately 20% by Mg2+, approximately 30% by S(+)-ketamine, and approximately 50% by the compounds in combination.
Negative_regulation (reduced) of concentration associated with ketamine
5) Confidence 0.00 Published 2001 Journal Anesth. Analg. Section Abstract Doc Link 11323344 Disease Relevance 0 Pain Relevance 0.69

General Comments

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