INT220437

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Context Info
Confidence 0.41
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.68
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (IL19) extracellular space (IL19) extracellular region (IL19)
Anatomy Link Frequency
MDA-MB-231 1
IL19 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 2 97.76 Very High Very High Very High
COX-2 inhibitor 40 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 124 96.96 Very High Very High Very High
INFLAMMATION 2 96.32 Very High Very High Very High
Breast Cancer 18 50.00 Quite Low
Cancer 24 5.00 Very Low Very Low Very Low
Ovarian Cancer 12 5.00 Very Low Very Low Very Low
Retinoblastoma 4 5.00 Very Low Very Low Very Low
Necrosis 4 5.00 Very Low Very Low Very Low
Reprotox - General 1 4 5.00 Very Low Very Low Very Low
Metastasis 2 5.00 Very Low Very Low Very Low
Hepatocellular Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Celecoxib downregulates COX-2 protein expression in MDA-MB-231 and MDA-MB-435 cells
Negative_regulation (downregulates) of MDA in MDA-MB-231
1) Confidence 0.41 Published 2007 Journal Breast Cancer Res Section Body Doc Link PMC2206712 Disease Relevance 0.40 Pain Relevance 0.10
COX-2 protein expression was also decreased in all MDA-MB-435 variants, with the percentages being 39% for MDA-MB-435 parental cells, 25% for the vector control cells, and 60% for the E1A stable transfectants (Figure 4A).
Negative_regulation (decreased) of MDA
2) Confidence 0.41 Published 2007 Journal Breast Cancer Res Section Body Doc Link PMC2206712 Disease Relevance 0.28 Pain Relevance 0.08

General Comments

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