INT220467

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Context Info
Confidence 0.07
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 1.47
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (BAG6) cytosol (BAG6) transport (BAG6)
nucleus (BAG6) embryo development (BAG6) cytoplasm (BAG6)
Anatomy Link Frequency
endothelial cells 2
BAG6 (Homo sapiens)
Pain Link Frequency Relevance Heat
anesthesia 4 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
Sciatic nerve 4 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Breast Cancer 140 99.52 Very High Very High Very High
Cancer 304 97.32 Very High Very High Very High
Osteolysis 56 57.80 Quite High
Metastasis 104 36.76 Quite Low
Apoptosis 20 34.24 Quite Low
Anaplastic Astrocytoma 8 25.28 Quite Low
Sprains And Strains 4 24.56 Low Low
Injury 20 8.72 Low Low
Adhesions 44 7.60 Low Low
Malignant Neoplastic Disease 20 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
G3 mediated effects on endothelial cells
Positive_regulation (mediated) of Gene_expression (effects) of G3 in endothelial cells
1) Confidence 0.07 Published 2007 Journal Breast Cancer Res Section Body Doc Link PMC2206723 Disease Relevance 0.38 Pain Relevance 0
The G3 construct and a control vector were stably transfected into human breast carcinoma MT-1 cells using Lipofectamine 2000.
Positive_regulation (transfected) of Gene_expression (transfected) of G3 associated with breast cancer
2) Confidence 0.07 Published 2007 Journal Breast Cancer Res Section Body Doc Link PMC2206723 Disease Relevance 0.54 Pain Relevance 0
This was consistent with the observation of increased versican G3 expression as assessed by immunoblotting in the experimental group following tumor tissue harvest when compared to the vector control group (Figure 2c).


Positive_regulation (increased) of Gene_expression (expression) of G3 associated with cancer
3) Confidence 0.07 Published 2007 Journal Breast Cancer Res Section Body Doc Link PMC2206723 Disease Relevance 0.41 Pain Relevance 0
Human MT-1 cells stably transfected with the G3 construct or the control vector were cultured at a density of 1 × 105 cells/ml/well on 12-well tissue culture plates in RPMI-1640 media (Life Technologies, Inc.
Positive_regulation (transfected) of Gene_expression (transfected) of G3
4) Confidence 0.07 Published 2007 Journal Breast Cancer Res Section Body Doc Link PMC2206723 Disease Relevance 0.14 Pain Relevance 0

General Comments

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