INT220567

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Context Info
Confidence 0.15
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.36
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
cleavage 4
Il1r2 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory response 4 82.64 Quite High
Inflammation 20 51.28 Quite High
cytokine 7 40.92 Quite Low
Central nervous system 11 35.36 Quite Low
ischemia 12 5.00 Very Low Very Low Very Low
Peripheral nervous system 10 5.00 Very Low Very Low Very Low
cINOD 9 5.00 Very Low Very Low Very Low
sodium channel 5 5.00 Very Low Very Low Very Low
Hippocampus 5 5.00 Very Low Very Low Very Low
Nav1.1 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 167 92.36 High High
INFLAMMATION 26 82.28 Quite High
Adhesions 2 50.64 Quite High
Drug Induced Neurotoxicity 2 34.60 Quite Low
Targeted Disruption 65 5.00 Very Low Very Low Very Low
Stress 57 5.00 Very Low Very Low Very Low
Alzheimer's Dementia 51 5.00 Very Low Very Low Very Low
Cognitive Disorder 34 5.00 Very Low Very Low Very Low
Hypoxia 32 5.00 Very Low Very Low Very Low
Syndrome 32 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cleavage of IL-1R2 by both BACE enzymes occurred at sites that agreed well with the known cleavage specificity of BACE1 and BACE2 and led to the generation of CTF that were similar to those generated by ?
Positive_regulation (occurred) of Positive_regulation (Cleavage) of IL-1R2 in cleavage
1) Confidence 0.15 Published 2007 Journal Mol Neurodegener Section Body Doc Link PMC2211305 Disease Relevance 0.08 Pain Relevance 0.04
Cleavage of IL-1R2 by both BACE enzymes occurred at sites that agreed well with the known cleavage specificity of BACE1 and BACE2 and led to the generation of CTF that were similar to those generated by ?
Positive_regulation (occurred) of Positive_regulation (Cleavage) of IL-1R2 in cleavage
2) Confidence 0.15 Published 2007 Journal Current Genomics Section Body Doc Link PMC2647160 Disease Relevance 0.28 Pain Relevance 0.07

General Comments

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