INT220629

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Context Info
Confidence 0.17
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.19
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Bace1) peptidase activity (Bace1) Golgi apparatus (Bace1)
endoplasmic reticulum (Bace1) enzyme binding (Bace1)
Bace1 (Mus musculus)
Il1r2 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory response 2 85.20 High High
Inflammation 9 50.96 Quite High
cytokine 4 40.64 Quite Low
Central nervous system 6 35.08 Quite Low
ischemia 7 5.00 Very Low Very Low Very Low
cINOD 6 5.00 Very Low Very Low Very Low
Peripheral nervous system 6 5.00 Very Low Very Low Very Low
sodium channel 3 5.00 Very Low Very Low Very Low
Hippocampus 3 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 13 84.84 Quite High
Adhesions 1 50.32 Quite High
Disease 14 50.00 Quite Low
Drug Induced Neurotoxicity 1 34.32 Quite Low
Targeted Disruption 34 5.00 Very Low Very Low Very Low
Stress 31 5.00 Very Low Very Low Very Low
Alzheimer's Dementia 29 5.00 Very Low Very Low Very Low
Cognitive Disorder 21 5.00 Very Low Very Low Very Low
Hypoxia 18 5.00 Very Low Very Low Very Low
Syndrome 17 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, the secretion of IL-1R2 was elevated by both BACE1 and BACE2 overexpression.
Gene_expression (overexpression) of BACE1 Positive_regulation (elevated) of Localization (secretion) of IL-1R2
1) Confidence 0.17 Published 2007 Journal Mol Neurodegener Section Body Doc Link PMC2211305 Disease Relevance 0.19 Pain Relevance 0.07

General Comments

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