INT220633

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Context Info
Confidence 0.09
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.32
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Kat5) nucleolus (Kat5) nucleus (Kat5)
transferase activity, transferring acyl groups (Kat5) protein complex (Kat5) transcription factor binding (Kat5)
Anatomy Link Frequency
nucleus 1
Kat5 (Mus musculus)
Ighd (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 6 66.80 Quite High
Inflammation 9 66.48 Quite High
cytokine 4 56.16 Quite High
Inflammatory response 2 43.52 Quite Low
ischemia 7 5.00 Very Low Very Low Very Low
cINOD 6 5.00 Very Low Very Low Very Low
Peripheral nervous system 6 5.00 Very Low Very Low Very Low
sodium channel 3 5.00 Very Low Very Low Very Low
Hippocampus 3 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Drug Induced Neurotoxicity 1 69.12 Quite High
INFLAMMATION 13 66.48 Quite High
Toxicity 2 64.72 Quite High
Alzheimer's Dementia 29 58.76 Quite High
Disease 14 50.00 Quite Low
Adhesions 1 36.72 Quite Low
Hypercholesterolemia 3 34.36 Quite Low
Targeted Disruption 34 5.00 Very Low Very Low Very Low
Stress 31 5.00 Very Low Very Low Very Low
Cognitive Disorder 21 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The LRP-ICD has been shown to translocate to the nucleus and interact with Fe65 and Tip60, although whether this occurs under physiological conditions remains to be determined.
Tip60 Binding (interact) of ICD in nucleus
1) Confidence 0.09 Published 2007 Journal Mol Neurodegener Section Body Doc Link PMC2211305 Disease Relevance 0.32 Pain Relevance 0.12

General Comments

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