INT220664

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Context Info
Confidence 0.10
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 5
Disease Relevance 1.23
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Mfi2) extracellular region (Mfi2) plasma membrane (Mfi2)
Anatomy Link Frequency
macrophages 4
peritoneal macrophages 2
Mfi2 (Mus musculus)
Pain Link Frequency Relevance Heat
ischemia 41 100.00 Very High Very High Very High
cytokine 63 86.20 High High
Inflammation 20 5.00 Very Low Very Low Very Low
Inflammatory response 10 5.00 Very Low Very Low Very Low
alcohol 4 5.00 Very Low Very Low Very Low
analgesia 4 5.00 Very Low Very Low Very Low
cva 3 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 21 100.00 Very High Very High Very High
Targeted Disruption 20 99.68 Very High Very High Very High
Coagulation Disorder 7 84.08 Quite High
Injury 26 78.48 Quite High
Lung Injury 7 77.68 Quite High
Stroke 72 50.00 Quite Low
Adult Respiratory Distress Syndrome 42 50.00 Quite Low
Necrosis 17 50.00 Quite Low
Cancer 17 50.00 Quite Low
Cv General 4 Under Development 9 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
MFI: 27 ± 2) than do macrophages (IL-1?
Positive_regulation (macrophages) of Gene_expression (do) of MFI in macrophages
1) Confidence 0.10 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2585073 Disease Relevance 0.11 Pain Relevance 0.06
(MFI: 85.28, (IgG: 49.23)) than did ischemia-activated macrophages (MFI: 104.03 (IgG: 46.06)) whereas LPS-stimulated peritoneal macrophages expressed higher levels of TNF-a (MFI: 53.84, (IgG: 14.79)) than did ischemia-activated macrophages (MFI: 39.28 (IgG: 24.11)).


Positive_regulation (activated) of Gene_expression (expressed) of MFI in macrophages associated with ischemia
2) Confidence 0.10 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2585073 Disease Relevance 0.27 Pain Relevance 0.21
Determination of the MFI showed that the LPS-stimulated peritoneal macrophages expressed lower levels of IL-1?
Positive_regulation (showed) of Gene_expression (Determination) of MFI in peritoneal macrophages
3) Confidence 0.10 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2585073 Disease Relevance 0.25 Pain Relevance 0.21
Generation of MFI values for TNF-?
Positive_regulation (Generation) of Gene_expression (Generation) of MFI
4) Confidence 0.10 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2585073 Disease Relevance 0.15 Pain Relevance 0
The tissue distribution and expression levels of hTF in transgenic mice were similar to that of mTF in wild type mice, and no mTF expression was detected in the transgenic mice [16].
Positive_regulation (detected) of Gene_expression (expression) of mTF associated with targeted disruption
5) Confidence 0.01 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2211395 Disease Relevance 0.44 Pain Relevance 0

General Comments

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