INT22076

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Context Info
Confidence 0.46
First Reported 1987
Last Reported 2010
Negated 0
Speculated 1
Reported most in Abstract
Documents 7
Total Number 8
Disease Relevance 2.90
Pain Relevance 0.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Mb)
Anatomy Link Frequency
blood 4
chest 2
molar 2
Mb (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Angina 8 99.12 Very High Very High Very High
halothane 4 75.04 Quite High
anesthesia 3 75.00 Quite High
cva 1 67.52 Quite High
Pain 1 44.08 Quite Low
ketamine 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myocardial Infarction 23 100.00 Very High Very High Very High
Angina 8 99.12 Very High Very High Very High
Malignant Hyperthermia 1 97.16 Very High Very High Very High
Infarction 2 96.32 Very High Very High Very High
Disease 3 86.88 High High
Cv Unclassified Under Development 3 82.08 Quite High
Necrosis 1 71.28 Quite High
Cv General 3 Under Development 1 67.52 Quite High
Arrhythmias 2 Under Development 1 66.88 Quite High
Injury 2 63.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The level of myoglobin in the blood of patients with primary transmural myocardial infarction was rapidly increased, reaching its maximum in 9-12 h and returning to normal in 9 days.
Positive_regulation (reaching) of Positive_regulation (increased) of myoglobin in blood associated with myocardial infarction
1) Confidence 0.46 Published 1987 Journal Ter. Arkh. Section Abstract Doc Link 3629507 Disease Relevance 0.53 Pain Relevance 0.03
The environment for the resulting “0 nsec” structure of dimer S-MB thus closely approximates that of our SDS-PAGE experiments, which similarly use a loading buffer containing submicellar SDS at a detergent/peptide molar ratio of ?
Positive_regulation (approximates) of Positive_regulation (environment) of dimer S-MB in molar
2) Confidence 0.39 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2805716 Disease Relevance 0 Pain Relevance 0
These results indicate that increases in Mb and CK values were mainly induced by SCC injection and that SCC might play some roles in development of malignant hyperthermia.
Positive_regulation (induced) of Positive_regulation (increases) of Mb associated with malignant hyperthermia
3) Confidence 0.37 Published 1990 Journal Masui Section Abstract Doc Link 2246808 Disease Relevance 0.10 Pain Relevance 0.27
Blood samples for measurement of myoglobin, creatine kinase isoform MB, and troponin T were obtained every 30 min during the first 3 h and then after successively longer intervals.
Positive_regulation (samples) of Positive_regulation (measurement) of myoglobin in Blood
4) Confidence 0.27 Published 1997 Journal Clin. Chem. Section Abstract Doc Link 9342013 Disease Relevance 0.53 Pain Relevance 0.10
In patients with acute myocardial infarction, the elevation of serum myoglobin preceded that of creatine kinase in most cases.
Positive_regulation (preceded) of Positive_regulation (elevation) of serum myoglobin associated with myocardial infarction
5) Confidence 0.26 Published 1988 Journal Arch. Intern. Med. Section Abstract Doc Link 3401097 Disease Relevance 1.03 Pain Relevance 0.06
HYPOTHESIS: We sought to test an algorithm for rapid diagnosis of MI and acute coronary syndromes using cardiac troponin I (cTnI) and myoglobin as adjuncts to creatine kinase (CK)-MB.
Positive_regulation (syndromes) of Positive_regulation (using) of myoglobin
6) Confidence 0.09 Published 2000 Journal Clin Cardiol Section Body Doc Link 11129678 Disease Relevance 0.09 Pain Relevance 0
HYPOTHESIS: We sought to test an algorithm for rapid diagnosis of MI and acute coronary syndromes using cardiac troponin I (cTnI) and myoglobin as adjuncts to creatine kinase (CK)-MB.
Positive_regulation (using) of Positive_regulation (adjuncts) of myoglobin
7) Confidence 0.09 Published 2000 Journal Clin Cardiol Section Body Doc Link 11129678 Disease Relevance 0.09 Pain Relevance 0
Early sensitivities of creatine kinase (CK), CKMB (activity and mass), CKMM and CKMB isoform ratios, myoglobin, cardiac troponin I (cTnI), and cardiac troponin T (cTnT) were compared to find the most sensitive serum marker for acute myocardial infarction (AMI) during the first hours after onset of chest pain.
Spec (find) Positive_regulation (find) of Positive_regulation (sensitivities) of myoglobin in chest associated with angina and myocardial infarction
8) Confidence 0.06 Published 1995 Journal Clin. Chem. Section Abstract Doc Link 7656437 Disease Relevance 0.53 Pain Relevance 0.17

General Comments

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