INT220792

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Context Info
Confidence 0.71
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 5
Disease Relevance 0.56
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Tert) chromosome (Tert) RNA binding (Tert)
nucleus (Tert) DNA binding (Tert) nucleotidyltransferase activity (Tert)
Tert (Mus musculus)
Pain Link Frequency Relevance Heat
withdrawal 4 5.00 Very Low Very Low Very Low
medulla 4 5.00 Very Low Very Low Very Low
Snapping jaw 4 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperplasia 1 94.16 High High
Aging 6 66.80 Quite High
Injury 17 64.48 Quite High
Cicatrix 4 60.00 Quite High
Cancer 25 32.68 Quite Low
Alopecia 34 15.84 Low Low
Infection 4 9.84 Low Low
Targeted Disruption 25 5.00 Very Low Very Low Very Low
Teratoma 24 5.00 Very Low Very Low Very Low
Wound Healing 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Myc and TERT are also linked in that Myc is thought to regulate TERT gene transcription, although this connection is insufficient to explain the similarity in gene expression profiles identified here.


Transcription (transcription) of TERT gene
1) Confidence 0.71 Published 2008 Journal PLoS Genetics Section Body Doc Link PMC2211538 Disease Relevance 0.09 Pain Relevance 0
Moreover, GFs consistently showed higher expression of Tert mRNA compared to TTFs.
Transcription (expression) of Tert
2) Confidence 0.37 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2939066 Disease Relevance 0.17 Pain Relevance 0
Tert is one of the major subunits in the telomerase complex [41], and the transcription of Tert gene correlates with telomerase activity in most cells [42].
Transcription (transcription) of Tert gene
3) Confidence 0.32 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2939066 Disease Relevance 0.30 Pain Relevance 0
Real-time RT-PCR showed that the expression level of telomerase reverse transcriptase (Tert) mRNA in pGFs and mGFs was maintained for 6 passages, while that in TTFs decreased as the passage number increased (Fig. 5C).
Transcription (level) of Tert
4) Confidence 0.31 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2939066 Disease Relevance 0 Pain Relevance 0
The endogenous mRNA expression of Oct3/4, Sox2, Klf4, c-Myc, p53, p21 and Tert in pGFs, mGFs and TTFs at passages 4 to 6 was determined by real-time RT-PCR analysis.
Transcription (expression) of Tert
5) Confidence 0.28 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2939066 Disease Relevance 0 Pain Relevance 0

General Comments

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