INT220796

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Context Info
Confidence 0.04
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.84
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transferase activity, transferring glycosyl groups (Art2b) plasma membrane (Art2b)
Anatomy Link Frequency
hair 1
skin 1
Art2b (Mus musculus)
Pain Link Frequency Relevance Heat
withdrawal 8 50.24 Quite High
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Alopecia 68 97.52 Very High Very High Very High
Targeted Disruption 50 95.60 Very High Very High Very High
Cancer 10 5.00 Very Low Very Low Very Low
Body Weight 4 5.00 Very Low Very Low Very Low
Adhesions 4 5.00 Very Low Very Low Very Low
Aging 4 5.00 Very Low Very Low Very Low
Hyperplasia 2 5.00 Very Low Very Low Very Low
Helminth Infection 2 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data show that RT activity is not required for induction of anagen when TERT is conditionally upregulated in mouse skin.


Positive_regulation (upregulated) of RT in skin
1) Confidence 0.04 Published 2008 Journal PLoS Genetics Section Body Doc Link PMC2211538 Disease Relevance 0.51 Pain Relevance 0.03
Together, these data show that RT activity is dispensable for TERT's effects in causing quiescent hair follicle stem cells to proliferate, in facilitating a developmental switch from telogen to anagen and in enabling hair growth.


Positive_regulation (dispensable) of RT in hair associated with alopecia
2) Confidence 0.03 Published 2008 Journal PLoS Genetics Section Body Doc Link PMC2211538 Disease Relevance 0.33 Pain Relevance 0

General Comments

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