INT220839

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Context Info
Confidence 0.29
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 7
Total Number 11
Disease Relevance 3.20
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
Nail 3
shaft 2
T cells 2
macrophages 1
monocytes 1
Cd244 (Mus musculus)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 174 96.04 Very High Very High Very High
cva 5 80.68 Quite High
Inflammation 24 36.40 Quite Low
methotrexate 24 20.36 Low Low
corticosteroid 24 17.20 Low Low
cINOD 18 12.68 Low Low
cytokine 18 5.00 Very Low Very Low Very Low
Lasting pain 15 5.00 Very Low Very Low Very Low
Pain 10 5.00 Very Low Very Low Very Low
chemokine 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hip Fractures 75 99.16 Very High Very High Very High
Cytomegalovirus Infection 282 97.12 Very High Very High Very High
Rheumatoid Arthritis 180 96.04 Very High Very High Very High
Myositis 6 94.52 High High
Stroke 5 84.84 Quite High
Renal Insufficiency 5 84.44 Quite High
Sepsis 5 83.60 Quite High
Deep Vein Thrombosis 5 81.68 Quite High
Cv General 3 Under Development 5 80.68 Quite High
Intraoperative Complications 5 73.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
NKB set up the flow cytometric assays for investigation of the CD244 expression.
Gene_expression (expression) of CD244
1) Confidence 0.29 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2212553 Disease Relevance 0.61 Pain Relevance 0.06
CD4dim macrophages/monocytes and NK cells [13], which also might express CD244, could be excluded using the combination of CD3 and CD4 in the three-colour stainings to identify CD4+ T cells.
Gene_expression (express) of CD244 in NK cells
2) Confidence 0.29 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2212553 Disease Relevance 0 Pain Relevance 0
Targeted distal nail locking in short nails (SGN and TGN) resulted in 8.6% misdrillings until 1993.
Gene_expression (locking) of nail in nails
3) Confidence 0.29 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2906434 Disease Relevance 0.49 Pain Relevance 0.04
"The Long Gamma Nail" (LGN) was introduced in 1992 and is used for subtrochanteric hip fractures, femoral shaft fractures and combined trochantero-diaphyseal fractures of the femur.
Gene_expression (used) of Nail in shaft associated with hip fractures
4) Confidence 0.29 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2906434 Disease Relevance 0.44 Pain Relevance 0
The Gamma Nail was developed for the treatment of trochanteric hip fractures in the mid 1980's and was first brought into clinical use in 1988.
Gene_expression (developed) of Nail in Nail associated with hip fractures
5) Confidence 0.29 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2906434 Disease Relevance 0.24 Pain Relevance 0
"The Long Gamma Nail" (LGN) was introduced in 1992 and is used for subtrochanteric hip fractures, femoral shaft fractures and combined trochantero-diaphyseal fractures of the femur.
Gene_expression (introduced) of Nail in shaft associated with hip fractures
6) Confidence 0.29 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2906434 Disease Relevance 0.44 Pain Relevance 0
On the other hand in a study of 1000 patients [28] and in a study on the second-generation Gamma Nail (TGN) [5] this complication had a low rate of 1.1% and 0% respectively.
Gene_expression (generation) of Nail in Nail
7) Confidence 0.26 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2906434 Disease Relevance 0.11 Pain Relevance 0
Instead of detecting T cells lacking CD28, CD4+CD28null T cells in synovial membrane biopsies were identified by co-expression of CD244, CD3 and CD4 (Figure 1).
Gene_expression (expression) of CD244 in T cells
8) Confidence 0.23 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2212553 Disease Relevance 0.27 Pain Relevance 0.04
This technique utilizes our findings of CD244 expression by CD4+ T cells as a specific marker for the CD28null subset in peripheral blood of patients with RA and muscle tissue of patients with myositis (Figure 1) (Fasth et al., submitted).
Gene_expression (expression) of CD244 in T cells associated with rheumatoid arthritis and myositis
9) Confidence 0.23 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2212553 Disease Relevance 0.60 Pain Relevance 0.05
CD4dim macrophages/monocytes and NK cells [13], which also might express CD244, could be excluded using the combination of CD3 and CD4 in the three-colour stainings to identify CD4+ T cells.
Gene_expression (express) of CD244 in monocytes
10) Confidence 0.10 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2212553 Disease Relevance 0 Pain Relevance 0
CD4dim macrophages/monocytes and NK cells [13], which also might express CD244, could be excluded using the combination of CD3 and CD4 in the three-colour stainings to identify CD4+ T cells.
Gene_expression (express) of CD244 in macrophages
11) Confidence 0.10 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2212553 Disease Relevance 0 Pain Relevance 0

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