INT220862

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Context Info
Confidence 0.05
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.41
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Ctsl) histone binding (Ctsl) nucleolus (Ctsl)
vacuole (Ctsl) lysosome (Ctsl) cytoplasm (Ctsl)
Ctsl (Mus musculus)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 38 85.84 High High
Arthritis 5 63.96 Quite High
metalloproteinase 64 40.64 Quite Low
cytokine 14 28.32 Quite Low
Osteoarthritis 19 22.72 Low Low
Inflammation 8 5.00 Very Low Very Low Very Low
Neuropeptide 2 5.00 Very Low Very Low Very Low
methotrexate 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 38 85.84 High High
Arthritis 6 63.96 Quite High
Congenital Anomalies 1 47.12 Quite Low
Disease 15 46.16 Quite Low
Fibrosarcoma 2 40.04 Quite Low
Skin Cancer 1 39.08 Quite Low
Reprotox - General 1 1 32.36 Quite Low
Osteoarthritis 19 22.72 Low Low
Malignant Neoplastic Disease 1 17.16 Low Low
Cancer 8 14.24 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In this regard, inhibition of cathepsin L by a specific ribozyme was able to reduce expression of cathepsin L mRNA to 44% [84].
Negative_regulation (reduce) of Transcription (expression) of cathepsin L
1) Confidence 0.05 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2212555 Disease Relevance 0.41 Pain Relevance 0.21

General Comments

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