INT220871

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.15
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Timp3, Adamts1) proteinaceous extracellular matrix (Timp3, Adamts1) peptidase activity (Adamts1)
cytoplasm (Timp3)
Timp3 (Mus musculus)
Adamts1 (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 64 99.70 Very High Very High Very High
Osteoarthritis 19 76.80 Quite High
rheumatoid arthritis 38 76.24 Quite High
cytokine 14 5.00 Very Low Very Low Very Low
Inflammation 8 5.00 Very Low Very Low Very Low
Arthritis 5 5.00 Very Low Very Low Very Low
Neuropeptide 2 5.00 Very Low Very Low Very Low
methotrexate 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 19 76.80 Quite High
Rheumatoid Arthritis 38 76.24 Quite High
Disease 15 5.00 Very Low Very Low Very Low
INFLAMMATION 10 5.00 Very Low Very Low Very Low
Cancer 8 5.00 Very Low Very Low Very Low
Arthritis 6 5.00 Very Low Very Low Very Low
Hypercalcemia 2 5.00 Very Low Very Low Very Low
Seronegative Spondarthritis 2 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Like MMPs, ADAMTS-4 and ADAMTS-5 are inhibited by TIMP-3 [29].



TIMP-3 Negative_regulation (inhibited) of ADAMTS associated with metalloproteinase
1) Confidence 0.01 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2212555 Disease Relevance 0.15 Pain Relevance 0.27

General Comments

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