INT22094

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Context Info
Confidence 0.42
First Reported 1987
Last Reported 1990
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 0.95
Pain Relevance 1.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (CTSG) extracellular space (CTSG) extracellular region (CTSG)
plasma membrane (CTSG)
Anatomy Link Frequency
granulocyte 2
neutrophil 1
CTSG (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 10 99.28 Very High Very High Very High
Pain 1 83.28 Quite High
headache 1 82.32 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 4 99.08 Very High Very High Very High
Syndrome 2 91.12 High High
Sweet's Syndrome 3 90.40 High High
Arthralgia 1 82.80 Quite High
Headache 1 82.32 Quite High
Fever 1 81.92 Quite High
Pressure And Volume Under Development 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In affected skin we applied immunohistochemical methods to examine the topographical organization of neutrophil-associated proteinase/proteinase inhibitor systems, i.e. the PMN-elastase/alpha 1-proteinase inhibitor and the cathepsin G/alpha 1-antichymotrypsin systems.
Negative_regulation (inhibitor) of cathepsin G in neutrophil
1) Confidence 0.42 Published 1990 Journal Hautarzt Section Abstract Doc Link 2249945 Disease Relevance 0.58 Pain Relevance 0.17
Inhibition of human granulocyte elastase and cathepsin G by non-steroidal anti-inflammatory drugs (NSAID)s.
Negative_regulation (Inhibition) of cathepsin G in granulocyte associated with inflammation and cinod
2) Confidence 0.42 Published 1987 Journal Biochem. Int. Section Title Doc Link 3440020 Disease Relevance 0.20 Pain Relevance 0.46
A series of non-steroidal anti-inflammatory drugs (NSAIDs) and some of their metabolites were evaluated for their ability to inhibit the proteolytic activity of human granulocyte elastase (HGE) and cathepsin G (HGC-G).
Negative_regulation (inhibit) of cathepsin G in granulocyte associated with inflammation and cinod
3) Confidence 0.42 Published 1987 Journal Biochem. Int. Section Abstract Doc Link 3440020 Disease Relevance 0.17 Pain Relevance 0.42

General Comments

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