INT220962

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Context Info
Confidence 0.46
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.58
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ighg1)
Ighg1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 21 93.20 High High
Arthritis 61 85.12 High High
cytokine 6 38.96 Quite Low
methotrexate 11 11.40 Low Low
dexamethasone 3 7.36 Low Low
rheumatoid arthritis 18 5.00 Very Low Very Low Very Low
tolerance 4 5.00 Very Low Very Low Very Low
adenocard 3 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 82 99.42 Very High Very High Very High
Sprains And Strains 17 94.60 High High
INFLAMMATION 21 93.20 High High
Autoimmune Disease 3 85.84 High High
Arthritis 75 85.12 High High
Systemic Lupus Erythematosus 1 81.52 Quite High
Anaphylaxis 1 77.64 Quite High
Peanut Hypersensitivity 1 73.88 Quite High
Hypersensitivity 61 72.24 Quite High
Immunization 25 71.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Fc sialyation of IgG1 results in a reduced binding affinity for the activating receptor Fc?
Positive_regulation (results) of Localization (sialyation) of IgG1
1) Confidence 0.46 Published 2010 Journal Clin Mol Allergy Section Body Doc Link PMC2914046 Disease Relevance 0.98 Pain Relevance 0.05
In late disease (6 to 8 weeks after onset), titres of both IgG1 and IgG2a/c had increased modestly in DBA/1 mice.
Positive_regulation (increased) of Localization (titres) of IgG1 associated with disease
2) Confidence 0.36 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2212575 Disease Relevance 1.60 Pain Relevance 0.33

General Comments

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