INT221

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Context Info
Confidence 0.02
First Reported 1977
Last Reported 1977
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 1.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Chd7, Th) cytosol (Th) mitochondrion (Th)
oxidoreductase activity (Th) helicase activity (Chd7) DNA binding (Chd7)
Anatomy Link Frequency
brain 1
Chd7 (Mus musculus)
Th (Mus musculus)
Pain Link Frequency Relevance Heat
Morphine 6 99.76 Very High Very High Very High
noradrenaline 1 99.76 Very High Very High Very High
Catecholamine 8 96.32 Very High Very High Very High
GABAergic 4 79.44 Quite High
agonist 1 64.32 Quite High
Clonidine 1 62.24 Quite High
narcan 1 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effects of morphine and AOAA on the turnover of brain catecholamines (CA) were determined by measuring both the accumulation of dopa after inhibition of central aromatic L-amino acid decarboxylase and by measuring the depletion of noradrenaline (NA) after inhibition of tyrosine hydroxylase by alpha-methyltyrosine (alpha-MT).
alpha-MT Negative_regulation (inhibition) of tyrosine hydroxylase in brain associated with catecholamine, noradrenaline and morphine
1) Confidence 0.02 Published 1977 Journal J. Neural Transm. Section Abstract Doc Link 18553 Disease Relevance 0 Pain Relevance 1.04

General Comments

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