INT221030

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.24
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (ELANE, CXCL10) signal transduction (CXCL10) extracellular space (CXCL10)
peptidase activity (ELANE) cell-cell signaling (CXCL10) cytoplasm (ELANE)
Anatomy Link Frequency
blood 1
ELANE (Homo sapiens)
CXCL10 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 49 90.12 High High
chemokine 42 51.20 Quite High
Inflammation 13 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Crohn's disease 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 49 90.12 High High
INFLAMMATION 16 5.00 Very Low Very Low Very Low
Disease 5 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low
Infection 2 5.00 Very Low Very Low Very Low
Neutrophil Disorders 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Crystal Associated Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Results summarized in Figure 1 show a highly upregulated expression of CCL3 and CCL18 mRNAs, a downregulation of CCL21 mRNA (Figure 1a) and an upregulation of CXCL8 and CXCL10 mRNAs (Figure 1b) in SF PMN from each patient in comparison with blood PMN from healthy donors.
PMN Positive_regulation (upregulation) of CXCL10 in blood
1) Confidence 0.01 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2212580 Disease Relevance 0.24 Pain Relevance 0.15

General Comments

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