INT221041

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Context Info
Confidence 0.47
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.08
Pain Relevance 0.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CCL18) extracellular space (CCL18) extracellular region (CCL18)
cell-cell signaling (CCL18)
Anatomy Link Frequency
joints 1
lung 1
Th2 cells 1
CCL18 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 45 99.92 Very High Very High Very High
fibrosis 21 99.26 Very High Very High Very High
chemokine 50 99.00 Very High Very High Very High
rheumatoid arthritis 49 98.40 Very High Very High Very High
Inflammatory response 3 47.76 Quite Low
imagery 10 5.00 Very Low Very Low Very Low
positron emission tomography 7 5.00 Very Low Very Low Very Low
cytokine 7 5.00 Very Low Very Low Very Low
aspirin 5 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Arthritis 1 99.92 Very High Very High Very High
Pulmonary Fibrosis 7 99.26 Very High Very High Very High
Rheumatoid Arthritis 49 98.40 Very High Very High Very High
Rhinitis 62 97.68 Very High Very High Very High
INFLAMMATION 51 97.16 Very High Very High Very High
Nasal Polyps 6 95.36 Very High Very High Very High
Chronic Sinusitis 14 94.52 High High
Eczema 31 91.16 High High
Interstitial Lung Diseases 32 82.80 Quite High
Disease 49 66.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CCL18 has already been recognized in tissues and joints of patients with RA.
CCL18 Binding (recognized) of in joints associated with rheumatoid arthritis
1) Confidence 0.47 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2212580 Disease Relevance 0.58 Pain Relevance 0.29
CCL18 and CCL22 are associated with chemoattraction of Th2 cells, which further amplify eosinophilic inflammation.
CCL18 Binding (associated) of in Th2 cells associated with rhinitis and inflammation
2) Confidence 0.37 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2897889 Disease Relevance 1.07 Pain Relevance 0.25
Is the lack of an animal model for lung fibrosis explained by the fact that a rodent counterpart for human CCL18 does not exist [29]?
CCL18 Binding (counterpart) of in lung associated with fibrosis and pulmonary fibrosis
3) Confidence 0.36 Published 2010 Journal Respir Res Section Body Doc Link PMC2907324 Disease Relevance 0.43 Pain Relevance 0.05

General Comments

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