INT221085

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Context Info
Confidence 0.56
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.47
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (GHRH, IGF1) extracellular region (GHRH, IGF1) signal transduction (IGF1)
cell-cell signaling (GHRH)
Anatomy Link Frequency
liver 4
GHRH (Homo sapiens)
IGF1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Fibrositis 31 95.52 Very High Very High Very High
Pain 13 92.60 High High
carpal tunnel syndrome 2 77.28 Quite High
tolerance 2 68.40 Quite High
tricyclic antidepressant 2 48.40 Quite Low
cytokine 3 47.96 Quite Low
Inflammation 14 47.56 Quite Low
sSRI 4 46.24 Quite Low
Opioid 2 45.52 Quite Low
Analgesic 2 44.96 Quite Low
Disease Link Frequency Relevance Heat
Frailty 35 99.92 Very High Very High Very High
Fibromyalgia 31 95.52 Very High Very High Very High
Reprotox - General 1 1 95.32 Very High Very High Very High
Obesity 8 94.40 High High
Pain 12 92.60 High High
Stress 1 92.40 High High
Syndrome 6 91.20 High High
Hyperglycemia 2 79.52 Quite High
Hyperlipidemia 1 78.80 Quite High
Gallstones 1 77.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Growth Hormone secreted by the pituitary acts on the liver and other tissues to stimulate the production of IGF-1 [17].
Growth Hormone Positive_regulation (stimulate) of Gene_expression (production) of IGF-1 in liver
1) Confidence 0.56 Published 2007 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2212629 Disease Relevance 1.22 Pain Relevance 0.41
Growth hormone exerts an indirect anabolic effect on muscle by stimulating production of IGF-1 in the liver.
Growth hormone Positive_regulation (stimulating) of Gene_expression (production) of IGF-1 in liver
2) Confidence 0.05 Published 2009 Journal Osteoporos Int Section Body Doc Link PMC2832869 Disease Relevance 0.25 Pain Relevance 0

General Comments

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