INT22110

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.23
First Reported 1984
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 7
Disease Relevance 2.45
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (PTGFR) plasma membrane (PTGFR) cytoplasm (PTGFR)
signal transducer activity (PTGFR)
PTGFR (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 2 99.02 Very High Very High Very High
Inflammation 25 90.04 High High
Inflammatory mediators 2 84.12 Quite High
Dismenorea 2 80.56 Quite High
cINOD 5 66.80 Quite High
Kinase C 15 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aneuploidy 110 99.80 Very High Very High Very High
Necrosis 1 92.28 High High
Cancer 96 91.92 High High
Genomic Instability 45 90.32 High High
INFLAMMATION 32 90.04 High High
Infection 2 76.48 Quite High
Polyploidy 40 72.04 Quite High
Dysmenorrhea 2 71.68 Quite High
Mouth Cancer 5 70.16 Quite High
Chromosomal Instability 5 41.36 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recent evidence suggests that oxytocin is most important for the initial phase of labour, whereas increased synthesis of PGF2 alpha is essential for the progression of labour.
Positive_regulation (increased) of Gene_expression (synthesis) of PGF2 alpha
1) Confidence 0.23 Published 1984 Journal Br J Obstet Gynaecol Section Abstract Doc Link 6091729 Disease Relevance 0.07 Pain Relevance 0.07
can induce multipolar mitosis and increase aneuploidy in cells transfected with the human FP receptor.
Positive_regulation (transfected) of Gene_expression (transfected) of FP receptor associated with aneuploidy
2) Confidence 0.22 Published 2005 Journal Cell Mol Life Sci Section Body Doc Link PMC2792351 Disease Relevance 1.40 Pain Relevance 0.23
Lower panels: the relative percentages of multipolar spindles and misaligned chromosomes in mitotic cells stably transfected with empty vector (pCEP4-HEK) or the human FP prostanoid receptor (hFP-HEK) after treatment with 1 µM PGF2?
Positive_regulation (after) of Gene_expression (transfected) of prostanoid receptor
3) Confidence 0.22 Published 2005 Journal Cell Mol Life Sci Section Body Doc Link PMC2792351 Disease Relevance 0.28 Pain Relevance 0
Lower panels: the relative percentages of multipolar spindles and misaligned chromosomes in mitotic cells stably transfected with empty vector (pCEP4-HEK) or the human FP prostanoid receptor (hFP-HEK) after treatment with 1 µM PGF2?
Positive_regulation (transfected) of Gene_expression (transfected) of prostanoid receptor
4) Confidence 0.22 Published 2005 Journal Cell Mol Life Sci Section Body Doc Link PMC2792351 Disease Relevance 0.28 Pain Relevance 0
Histograms of cell cycle distributions of HEK cells stably transfected with either the human FP prostanoid receptor (hFP-HEK) or with the empty vector (pCEP4-HEK) and treated with either vehicle (2% Na2CO3) or 1 µM PGF2?
Positive_regulation (transfected) of Gene_expression (transfected) of prostanoid receptor
5) Confidence 0.22 Published 2005 Journal Cell Mol Life Sci Section Body Doc Link PMC2792351 Disease Relevance 0 Pain Relevance 0
treatment of HEK cells stably expressing the human FP prostanoid receptor increases expression of cyclin B1 (A) and increases Cdc2-mediated phosphorylation of histone H1 (B).
Positive_regulation (increases) of Gene_expression (expressing) of prostanoid receptor
6) Confidence 0.22 Published 2005 Journal Cell Mol Life Sci Section Body Doc Link PMC2792351 Disease Relevance 0 Pain Relevance 0
Endotoxin and these cytokines all induced significant concentration-dependent increases in PGE2 and PGF2 alpha production.
Positive_regulation (increases) of Gene_expression (production) of PGF2 associated with cytokine
7) Confidence 0.22 Published 1990 Journal Prostaglandins Leukot. Essent. Fatty Acids Section Abstract Doc Link 2251294 Disease Relevance 0.42 Pain Relevance 0.26

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox