INT221181

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.06
Pain Relevance 2.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (GOPC, Flna) plasma membrane (GOPC, Flna) Golgi apparatus (GOPC)
signal transducer activity (Flna) cytosol (Flna) nucleus (Flna)
GOPC (Homo sapiens)
Flna (Rattus norvegicus)
Pain Link Frequency Relevance Heat
narcan 216 100.00 Very High Very High Very High
mu opioid receptor 188 100.00 Very High Very High Very High
Morphine 70 96.56 Very High Very High Very High
antagonist 32 82.80 Quite High
Opioid 100 62.16 Quite High
addiction 28 57.96 Quite High
tolerance 40 57.36 Quite High
Analgesic 10 56.96 Quite High
analgesia 20 55.84 Quite High
opioid receptor 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuroblastoma 2 55.32 Quite High
Skin Cancer 6 44.28 Quite Low
Pain 2 5.00 Very Low Very Low Very Low
Hyperalgesia 2 5.00 Very Low Very Low Very Low
Decapitation 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 2 5.00 Very Low Very Low Very Low
Drug Dependence 2 5.00 Very Low Very Low Very Low
Vibrio Infection 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The final probing with a specific anti-FLNA antibody showed that FLNA associates with Go-coupled MOR and not with Gs-coupled MOR (Fig. 1 A,B).
Fig Neg (not) Binding (associates) of FLNA associated with mu opioid receptor
1) Confidence 0.03 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2212716 Disease Relevance 0 Pain Relevance 1.38
Both FLNA2556–2565 and FLNA2561–2570 markedly attenuated [3H]NLX binding to A7 cell membranes and to purified human FLNA (Fig. 4).
Fig Binding (binding) of FLNA2561 associated with narcan
2) Confidence 0.02 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2212716 Disease Relevance 0.06 Pain Relevance 0.70

General Comments

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