INT221183

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 1.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (OPRM1) endoplasmic reticulum (OPRM1) plasma membrane (OPRM1)
signal transducer activity (OPRM1)
OPRM1 (Homo sapiens)
Mors1 (Mus musculus)
Pain Link Frequency Relevance Heat
mu opioid receptor 94 100.00 Very High Very High Very High
narcan 108 96.64 Very High Very High Very High
Opioid 50 86.92 High High
Spinal cord 3 83.76 Quite High
MU agonist 1 66.40 Quite High
tolerance 20 62.68 Quite High
antagonist 16 52.72 Quite High
opiate 2 45.80 Quite Low
Morphine 35 31.32 Quite Low
opioid receptor 4 27.76 Quite Low
Disease Link Frequency Relevance Heat
Skin Cancer 3 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Hyperalgesia 1 5.00 Very Low Very Low Very Low
Neuroblastoma 1 5.00 Very Low Very Low Very Low
Decapitation 1 5.00 Very Low Very Low Very Low
Injury 1 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 1 5.00 Very Low Very Low Very Low
Drug Dependence 1 5.00 Very Low Very Low Very Low
Vibrio Infection 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since NLX prevents MOR–Gs coupling at concentrations well below its affinity for MOR and by influencing the coupling behavior of MORs, we considered proteins that interact with MOR and MOR-associated G proteins as the most likely targets, particularly those able to interact with multiple MORs.
MOR Binding (interact) of MORs associated with mu opioid receptor and narcan
1) Confidence 0.00 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2212716 Disease Relevance 0 Pain Relevance 1.12

General Comments

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