INT221194

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Context Info
Confidence 0.11
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.62
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Gja3) plasma membrane (Gja3)
Anatomy Link Frequency
hearts 2
Gja3 (Mus musculus)
Pain Link Frequency Relevance Heat
Kinase C 38 99.52 Very High Very High Very High
ischemia 3 95.24 Very High Very High Very High
Action potential 1 71.00 Quite High
potassium channel 76 41.92 Quite Low
adenocard 4 5.00 Very Low Very Low Very Low
action potential duration 4 5.00 Very Low Very Low Very Low
bradykinin 3 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
noradrenaline 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 68 100.00 Very High Very High Very High
Reperfusion Injury 30 97.40 Very High Very High Very High
Injury 6 92.16 High High
Parkinson's Disease 116 62.24 Quite High
Stress 19 5.00 Very Low Very Low Very Low
Apoptosis 16 5.00 Very Low Very Low Very Low
Targeted Disruption 8 5.00 Very Low Very Low Very Low
Death 5 5.00 Very Low Very Low Very Low
Thrombosis Related Under Development 4 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Studies in both pig and rat hearts demonstrated that the dephosphorylation of Cx43 and electrical uncoupling during ischaemia were prevented by IP in a PKC-dependent manner and that IP increased the co-localization of several protein kinases with Cx43 during ischemia [262,263].
Negative_regulation (prevented) of Phosphorylation (dephosphorylation) of Cx43 in hearts associated with kinase c, ischemia and cv unclassified under development
1) Confidence 0.11 Published 2007 Journal Biochimica et Biophysica Acta Section Body Doc Link PMC2212780 Disease Relevance 0.62 Pain Relevance 0.22

General Comments

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