INT221223

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.16
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (VDAC1) plasma membrane (VDAC1) transmembrane transport (VDAC1)
Anatomy Link Frequency
pore 1
VDAC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Kinase C 76 99.52 Very High Very High Very High
adenocard 8 48.48 Quite Low
bradykinin 6 47.60 Quite Low
noradrenaline 2 46.64 Quite Low
Opioid 2 45.20 Quite Low
antagonist 2 39.52 Quite Low
agonist 4 38.88 Quite Low
potassium channel 152 5.00 Very Low Very Low Very Low
action potential duration 8 5.00 Very Low Very Low Very Low
ischemia 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Parkinson's Disease 232 100.00 Very High Very High Very High
Reperfusion Injury 60 92.44 High High
Apoptosis 32 91.24 High High
Targeted Disruption 16 87.36 High High
Cv Unclassified Under Development 136 77.84 Quite High
Stress 38 61.92 Quite High
Hypoxia 2 55.92 Quite High
Necrosis 6 14.00 Low Low
Injury 12 5.00 Very Low Very Low Very Low
Death 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
involving phosphorylation of components of the MPTP such as the voltage dependent anion channel (VDAC) [113–115].
Phosphorylation (phosphorylation) of VDAC associated with parkinson's disease
1) Confidence 0.01 Published 2007 Journal Biochimica et Biophysica Acta Section Body Doc Link PMC2212780 Disease Relevance 0.54 Pain Relevance 0.63
has been reported to phosphorylate VDAC, and that this phosphorylation is associated with a sensitisation to cytotoxic drugs that stimulate pore opening [132].
Phosphorylation (phosphorylate) of VDAC in pore
2) Confidence 0.01 Published 2007 Journal Biochimica et Biophysica Acta Section Body Doc Link PMC2212780 Disease Relevance 0.61 Pain Relevance 0

General Comments

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