INT221234

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Context Info
Confidence 0.08
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.58
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

phosphatase activity (Ptpn2) transport (Gja3) endoplasmic reticulum (Ptpn2)
nucleus (Ptpn2) plasma membrane (Gja3) cytoplasm (Ptpn2)
Gja3 (Mus musculus)
Ptpn2 (Mus musculus)
Pain Link Frequency Relevance Heat
ischemia 3 88.20 High High
Kinase C 38 83.72 Quite High
Action potential 1 50.80 Quite High
potassium channel 76 21.72 Low Low
adenocard 4 5.00 Very Low Very Low Very Low
action potential duration 4 5.00 Very Low Very Low Very Low
bradykinin 3 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
noradrenaline 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Parkinson's Disease 116 100.00 Very High Very High Very High
Reperfusion Injury 30 92.24 High High
Cv Unclassified Under Development 68 88.20 High High
Injury 6 71.96 Quite High
Stress 19 5.00 Very Low Very Low Very Low
Apoptosis 16 5.00 Very Low Very Low Very Low
Targeted Disruption 8 5.00 Very Low Very Low Very Low
Death 5 5.00 Very Low Very Low Very Low
Thrombosis Related Under Development 4 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data imply a link between Cx43 and preconditioning and thus that Cx43 can in some way influence the opening of the MPTP, perhaps by a signalling mechanism involving ROS.
Cx43 Regulation (influence) of MPTP Binding (opening) of associated with parkinson's disease
1) Confidence 0.08 Published 2007 Journal Biochimica et Biophysica Acta Section Body Doc Link PMC2212780 Disease Relevance 0.58 Pain Relevance 0.18

General Comments

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